| Purine metabolism | Anabolism R5P→IMP: Ribose-phosphate diphosphokinase Amidophosphoribosyltransferase Phosphoribosylglycinamide formyl transferase AIR synthetase (FGAM cyclase) Phosphoribosylaminoimidazole carboxylase Phosphoribosylaminoimidazolesuccinocarboxamide synthase IMP synthase IMP→AMP: Adenylosuccinate synthase Adenylosuccinate lyase reverse AMP deaminase IMP→GMP: IMP dehydrogenase GMP synthase reverse GMP reductase Nucleotide salvage Hypoxanthine-guanine phosphoribosyltransferase Adenine phosphoribosyltransferase Catabolism Adenosine deaminase Purine nucleoside phosphorylase Guanine deaminase Xanthine oxidase Urate oxidase |
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| Pyrimidine metabolism | Anabolism CAD Carbamoyl phosphate synthase II Aspartate carbamoyltransferase Dihydroorotase Dihydroorotate dehydrogenase Orotidine 5′-phosphate decarboxylase/Uridine monophosphate synthetase CTP synthetase Catabolism Dihydropyrimidine dehydrogenase Dihydropyrimidinase/DPYS Beta-ureidopropionase/UPB1 |
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| Deoxyribonucleotides | Ribonucleotide reductase Nucleoside-diphosphate kinase DCMP deaminase Thymidylate synthase Dihydrofolate reductase |
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