Detyrosination is a form of posttranslational modification that occurs on alpha-tubulin. It consists of the removal of the C-terminal tyrosine to expose a glutamate at the newly formed C-terminus. Tubulin polymers, called microtubules, that contain detyrosinated alpha-tubulin are usually referred… Read more.

4.1.1: Carboxy-lyases Acetoacetate decarboxylase Adenosylmethionine decarboxylase Arginine decarboxylase Aromatic L-amino acid decarboxylase Glutamate decarboxylase Histidine decarboxylase Lysine decarboxylase Malonyl-CoA decarboxylase Ornithine decarboxylase Oxaloacetate decarboxylase Phosphoenolpyruvate carboxykinase Phosphoenolpyruvate carboxylase Phosphoribosylaminoimidazole carboxylase Pyrophosphomevalonate… Read more.

Purine metabolism Anabolism R5P→IMP: Ribose-phosphate diphosphokinase Amidophosphoribosyltransferase Phosphoribosylglycinamide formyl transferase AIR synthetase (FGAM cyclase) Phosphoribosylaminoimidazole carboxylase Phosphoribosylaminoimidazolesuccinocarboxamide synthase IMP synthase IMP→AMP: Adenylosuccinate synthase Adenylosuccinate lyase reverse AMP deaminase IMP→GMP: IMP dehydrogenase… Read more.

The enzyme Uridine monophosphate synthase (EC4.1.1.23, UMPS) (orotate phosphoribosyl transferase and orotidine-5′-decarboxylase) catalyses the formation of uridine monophosphate (UMP), an energy-carrying molecule in many important biosynthetic pathways.[5] In humans, the gene that codes for this enzyme is located on the… Read more.

Sucrose, transport(extracellular) Disaccharide catabolism – Congenital alactasia Sucrose intolerance Monosaccharide transport – Glucose-galactose malabsorption Inborn errors of renal tubular transport (Renal glycosuria) Fructose malabsorption Hexose → glucose Monosaccharide catabolism – Fructose: Essential fructosuria Fructose intolerance Galactose/galactosemia:… Read more.

Glycogen storage disease type II, also called Pompe disease, is an autosomal recessive metabolic disorder[1] which damages muscle and nerve cells throughout the body. It is caused by an accumulation of glycogen in the lysosome due to deficiency… Read more.

Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias.[4] This includes ventricular tachycardia (VT), ventricular fibrillation (VF), and wide complex tachycardia, as well as atrial fibrillation and paroxysmal supraventricular tachycardia.[4] Evidence in cardiac arrest, however, is poor.[5] It… Read more.

mDia1 (also known as Dia1, Drf1 for Diaphanous-related formin-1, Diaph1, KIAA4062, p140mDia, mKIAA4062, or D18Wsu154e) is a member of the protein family called the formins and is a Rho effector. It is the mouse version of the diaphanous homolog 1 of Drosophila.… Read more.