Physiology
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Aniline, through its conversion into antiandrogenic paracetamol (acetaminophen, tylenol), impairs male reproductive development
Industrial use of aniline is increasing worldwide with production estimated to surpass 5.6 million metric tons in 2016. Exposure to aniline occurs via air, diet, and water augmenting the risk… Read more.
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Osteopontin (OPN)
Osteopontin (OPN), also known as bone /sialoprotein I (BSP-1 or BNSP), early T-lymphocyte activation (ETA-1), secreted phosphoprotein 1 (SPP1), 2ar and Rickettsia resistance (Ric), is a protein that in humans is encoded by the SPP1 gene (secreted phosphoprotein 1). The murine ortholog is Spp1. Osteopontin is a SIBLING (glycoprotein) that was… Read more.
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Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. HIT predisposes to thrombosis (the abnormal formation of blood clots inside a blood vessel).
When thrombosis is identified the condition is called heparin-induced thrombocytopenia and thrombosis (HITT). HIT is caused by the formation of abnormal antibodies that activate platelets, which release microparticles that activate thrombin, leading to thrombosis. If someone receiving… Read more.
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Protamine sulfate is a medication that is used to reverse the effects of heparin and reported to cause allergic reactions in patients who are allergic to fish, diabetics using insulin preparations containing protamine, and vasectomized or infertile men
Protamine sulfate is a medication that is used to reverse the effects of heparin. It is specifically used in heparin overdose, in low molecular weight heparin overdose, and to reverse the effects of heparin during delivery and heart… Read more.
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Sex Disparity in Published Studies of IgE-mediated Food Allergy (among children with food allergies, 64.35% were males and 35.65% were females, among adults 34.82% were males and 65.18% were females)
Food allergies are potentially fatal immune-mediated disorders that are growing globally. The relationship between sex and food allergy remains incompletely understood. Here we tested the hypothesis that, should sex influence… Read more.
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The PVN Powerhouse: How the Paraventricular Nucleus Rules Hormone Secretion
Hold onto your hypothalamus, folks! We’re about to dive into the wild world of the Paraventricular Nucleus (PVN), where tiny cells pack a mighty hormonal punch! Picture this: deep in… Read more.
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Zinc, maybe
No proof for the need of zinc in human cells was shown until the late 1930s. More than most ever wanted to know about zinc. A work in progress. Read more.
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Freeze branding aka CryoBranding and the resulting brands, trichoglyphs, is a technique involving a cryogenic coolant instead of heat to produce permanent marks on a variety of animals
The coolant is used to lower the temperature of a branding iron such that its application to shaved skin will permanently alter hair follicles. The intense cold destroys the pigmentation apparatus in the animal’s hair follicles, leaving all subsequent hair growth… Read more.
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Light and Medical Tests
From Ask a Scientist: “Serum and plasma both come from the liquid portion of the blood that remains once the cells are removed, but that’s where the similarities end. Serum is… Read more.
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Nabil M. Elkassabany, Geralyn M. Meny, Rafael R. Doria, Catherine Marcucci; Green Plasma—Revisited. Anesthesiology 2008; 108:764–765 doi: https://doi.org/10.1097/ALN.0b013e3181672668
We could find no reports on green plasma in the past 40 yr in either the surgical or the anesthesia literature, which perhaps explains the lack of knowledge on the… Read more.
