Physiology
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Snake Venom: The Hormone Hijacker 馃悕
Imagine a villainous mastermind that can infiltrate your body’s hormonal headquarters, manipulating the delicate balance of estrogen and other hormones. Welcome to the world of snake venom, where the stakes… Read more.
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Intriguing Similarities Between Blood Clotting Issues Associated with Birth Control and Those Caused by Venomous Snake Bites
Estrogen effects: Birth control pills containing estrogen can increase blood clotting factors, potentially leading to an increased risk of blood clots. Similarly, some snake venoms contain components that can activate the… Read more.
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Relaxin
We’re about to dive into the wild world of Relaxin, the protein hormone that’s been turning heads since 1926 when Frederick Hisaw first stumbled upon it. This isn’t your average… Read more.
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HFE H63D & VO2聽max
SMOKE EM IF YOU GOT EM The聽HFE H63D聽is a聽single-nucleotide polymorphism聽in the聽HFE gene聽(c.187C>G, rs1799945), which results in the substitution of a histidine for an aspartic acid at amino acid position 63… Read more.
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“Hormesis” Derives from聽Greek聽H贸rm膿sis聽for “Rapid Motion, Eagerness”, Itself From Ancient Greek聽Horm谩ein聽to Excite.聽The Same Greek Root Provides the Word聽Hormone
Hormesis聽is a two-phased聽dose-response relationship聽to an environmental agent whereby low-dose amounts have a beneficial effect and high-dose amounts are either inhibitory to function or toxic.聽Within the聽hormetic zone, the biological response to… Read more.
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Marx SO, Reiken S, Hisamatsu Y, Gaburjakova M, Gaburjakova J, Yang YM, Rosemblit N, Marks AR. Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers. J Cell Biol. 2001 May 14;153(4):699-708. doi: 10.1083/jcb.153.4.699. PMID: 11352932; PMCID: PMC2192391.
Abstract Ryanodine receptors (RyRs), intracellular calcium release channels required for cardiac and skeletal muscle contraction, are macromolecular complexes that include kinases and phosphatases. Phosphorylation/dephosphorylation plays a key role in regulating… Read more.
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Oxytocin: The Molecular Maestro of Love and Labor
Buckle up, hormone enthusiasts. We’re about to take a wild ride into the world of oxytocin, the “love hormone” that’s been playing Cupid in our bodies since the dawn of… Read more.
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Omenn Syndrome: When Your Body Throws Its Own Surprise Party
Imagine your immune system as an overzealous party planner, but instead of organizing a fun bash, it’s staging a revolt against your own body. Welcome to the world of Omenn… Read more.
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Graft-versus-host disease (GvHD) is divided into聽acute聽and聽chronic聽forms
Graft-versus-host disease聽(GvHD) is a聽syndrome, characterized by inflammation in different organs. GvHD is commonly associated with聽bone marrow transplants聽and聽stem cell transplants. Not to be confused with聽Host-versus-graft disease. White blood cells聽of the donor’s… Read more.
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In the case of GVHD, maculopapular rash may progress to a condition similar to toxic epidermal necrolysis (TEN)
Together with Stevens鈥揓ohnson syndrome (SJS) it forms a spectrum of disease, with TEN being more severe. Early symptoms include fever and flu-like symptoms. A few days later the skin begins to blister and peel forming… Read more.
