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We’re Not Just Tough on Crime, We’re Addicted to It
The 1980s and 1990s were a golden era for those who believe that the path to a just society is paved with prison cells and cheap labor. Let us embark on a journey through this misguided epoch, where the so-called “tough on crime” policies collided spectacularly with the age-old American tradition of exploiting captive labor.
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Chalone Rangers: The Tissue-Specific Mitotic Inhibitors You Never Knew You Needed
Chalones are the unsung heroes of cellular crowd control. These tissue-specific, water-soluble substances are like the bouncers of your body, standing at the gates of mitosis with their arms crossed, saying, “Not tonight, buddy.” They’re the biochemical equivalent of that one friend who knows when to call it a night before things get out of
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Autacoids Unleashed: The Self-Made, Self-Destructive Hormones You Didn’t Know You Needed
What Are Autacoids? Autacoids (or autocoids) are the body’s DIY hormones—locally produced, short-lived biochemical messengers that scream, “I got this!” before promptly fading into oblivion. The term comes from the Greek autos (self) and acos (relief or drug), which is ironic because they’re basically the overachieving interns of the body: they do all the work locally, get no credit,
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Snake Venom: A Timeless Fascination
The history of humans studying snake venom is as fascinating as the venom itself, stretching back thousands of years. Let’s take a journey through time to explore how venom has captivated and terrified humanity, and how our understanding has evolved. Ancient Beginnings: Venom as Weapon and Medicine Humans have been aware of venom’s power since
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Snake Venom Can Have Significant Effects on Fat Distribution and Adipose Tissue
Stimulation of adipose tissue cells: Bothrops moojeni snake venom (Bmv) has been shown to stimulate preadipocytes, which are precursor cells to fat cells. This stimulation leads to the release of inflammatory mediators such as PGE2, IL-6, and KC/IL-8. Increased lipid accumulation: Bmv has been observed to increase lipid accumulation in preadipocytes, suggesting that it can
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Snake Venom: The Hormone Hijacker 🐍
Imagine a villainous mastermind that can infiltrate your body’s hormonal headquarters, manipulating the delicate balance of estrogen and other hormones. Welcome to the world of snake venom, where the stakes are high and the effects are unpredictable. Estrogen’s Uninvited Guest: When Snake Venom Crashes the Hormone Hoedown Prepare for the most bizarre gatecrasher at the
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Envenomation During Pregnancy Is Associated with Increased Risks Including Miscarriage
Several studies and case reports indicate that snake envenomation during pregnancy is associated with an increased risk of adverse outcomes, including miscarriage: Spontaneous abortions: Multiple studies report high rates of spontaneous abortions following venomous snake bites in pregnant women. One study found that nearly 30% of envenomated pregnant mothers experienced a spontaneous abortion. Fetal loss:
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Intriguing Similarities Between Blood Clotting Issues Associated with Birth Control and Those Caused by Venomous Snake Bites
Estrogen effects: Birth control pills containing estrogen can increase blood clotting factors, potentially leading to an increased risk of blood clots. Similarly, some snake venoms contain components that can activate the blood clotting system. Dual mechanisms: Both birth control and certain snake venoms can affect blood clotting in opposing ways: Birth control can increase clotting risk,
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Contraceptive Effects of Thermolysin?
We can draw some interesting connections based on the available information: Metalloproteinases: Thermolysin is a metalloproteinase, similar to the ADAM proteins and snake venom metalloproteinases (SVMPs) in other notes. These proteins share structural similarities and may have related functions. Potential interference with reproduction: Given that some metalloproteinases can interfere with reproductive processes, it’s possible that
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Snake Venom as Birth Control?
The research suggests some intriguing connections between snake venom components and reproductive processes: Reproductive dysfunction: Studies on Echis ocellatus venom show it can induce reproductive dysfunction in male rats, affecting sperm parameters, hormone levels, and reproductive organ tissues. ADAM protein family: Snake venom metalloproteinases (SVMPs) are closely related to ADAM (A Disintegrin And Metalloproteinase) proteins,
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