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Quasiracemate – Racemic mixture
There are four ways to crystallize a racemate; three of which H. W. B. Roozeboom had distinguished by 1899 and this is one of them. QuasiracemateA quasiracemate is a co-crystal of two similar but distinct compounds, one of which is left-handed and the other right-handed. Although chemically different, they are sterically similar (isosteric) and are still able
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Staphylokinase (SAK) AKA Staphylococcal Fibrinolysin or Müller’s Factor
Staphylokinase (SAK; also known as staphylococcal fibrinolysin or Müller’s factor) is a protein produced by Staphylococcus aureus. It contains 136 amino acid residues and has a molecular mass of 15kDa. Synthesis of staphylokinase occurs in late exponential phase. It is similar to streptokinase. Fibrinolysin is an enzyme derived from plasma of bovine origin (plasmin) or extracted from cultures of certain bacteria. (more below) Staphylokinase is positively
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Leavell, B S. “Thomas Jefferson and smallpox vaccination.” Transactions of the American Clinical and Climatological Association vol. 88 (1977): 119-27 and a few notes
Little Turtle, mentioned in the main article, suffered gout and rheumatism before he died in 1812 Wikipedia says Little Turtle, who also met Washington and Adams, made two trips to Washington, D.C., in 1801–02 and 1809–09 to meet with President Jefferson. Little Turtle died on July 14, 1812, and had suffered from gout and rheumatism for some time. He was honored
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Reactive Arthritis AKA Reiter’s Syndrome
Reportedly triggered by everything from food poisoning to bug bites to STDs to hormones (estrogen, relaxin) Mnemonic: Can't See, Can't Pee, Can't Climb a Tree
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DREAM complex
The dimerization partner, RB-like, E2F and multi-vulval class B (DREAM) complex is a protein complex responsible for the regulation of cell cycle-dependent gene expression. The complex is evolutionarily conserved, although some of its components vary from species to species. In humans, the key proteins in the complex are RBL1 (p107) and RBL2 (p130), both of which are homologs of RB (p105) and bind repressive E2F
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Retinoblastoma Protein Wiki
Retinoblastoma protein, dysfunctional in several cancers, belongs to the pocket protein family and is a recruiter of chromatin remodeling enzymes
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Chrysiasis
Chrysiasis is a dermatological condition induced by the parenteral administration of gold salts, usually for the treatment of rheumatoid arthritis. Such treatment has been superseded as the best practice for treating the disease because of “numerous side effects and monitoring requirements, their limited efficacy, and very slow onset of action”. Similar to silver, a gold preparation used parenterally for a long period may rarely
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Cathepsin G
Cathepsin G plays an important role in eliminating intracellular pathogens and breaking down tissues at inflammatory sites, as well as in anti-inflammatory response
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Acid phosphatase (systematic name phosphate-monoester phosphohydrolase (acid optimum)) is an enzyme that frees attached phosphoryl groups from other molecules during digestion
Acid phosphatase (EC 3.1.3.2, systematic name phosphate-monoester phosphohydrolase (acid optimum)) is an enzyme that frees attached phosphoryl groups from other molecules during digestion. It can be further classified as a phosphomonoesterase. It is stored in lysosomes and functions when these fuse with endosomes, which are acidified while they function; therefore, it has an acid pH optimum. This enzyme is present in many animal and plant
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